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Home » Products » Anti Cancer Medicines » Tasigna Nilotinib

Tasigna Nilotinib

Tasigna Nilotinib
Tasigna Nilotinib
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Product Code : 196
Brand Name : Tasigna
Product Description

Tasigna  (Nilotinib)

  • Brand name: Tasigna
  • Active Ingeridents (Generic Name) : Nilotinib
  • Company Name: Novartis
  • Package: 28 capsules
  • Strength : 150mg

Indication:

Tasigna (Nilotinib) is used to treat a certain type of blood cancer (chronic myelogenous leukemia-CML). It works by slowing or stopping the growth of cancer cells.

Mechanism of action:

Chronic myelogenous leukaemia (CML) is caused by the BCR-ABL oncogene. Tasigna (Nilotinib) inhibits the tyrosine kinase activity of the BCR-ABL protein. Tasigna (Nilotinib) fits into the ATP-binding site of the BCR-ABL protein with higher affinity than imatinib, over-riding resistance caused by mutations. The ability of AMN107 to inhibit TEL-platelet-derived growth factor receptor-beta (TEL-PDGFRbeta), which causes chronic myelomonocytic leukaemia, and FIP1-like-1-PDGFRalpha, which causes hypereosinophilic syndrome, suggests potential use of AMN107 for myeloproliferative diseases characterised by these kinase fusions (Stover et al, 2005; Weisberg et al, 2005). AMN107 also inhibits the c-Kit receptor kinase, including the D816V-mutated variant of KIT, at pharmacologically achievable concentrations, supporting potential utility in the treatment of mastocytosis, and gastrointestinal stromal tumours (Weisberg et al, 2005; von Bubnoff et al, 2005; Gleixner et al, 2006).

Dosage and Administration:

Tasigna (Nilotinib) is usually taken every 12 hours. Follow the directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take this medicine with a full glass of water. Swallow the capsule whole.

Take Tasigna (Nilotinib) on an empty stomach, at least 1 hour before or 2 hours after a meal. Do not take with food. Food can increase your blood levels of Tasigna (Nilotinib) and may increase your risk of harmful side effects.

Avoid eating anything for at least 2 hours before and 1 hour after you take Tasigna (Nilotinib).

Side effects:

Nausea, vomiting, headache, tiredness, constipation, and diarrhea may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Precaution:

Before taking Tasigna (Nilotinib), tell your doctor or pharmacist if you are allergic to it; or to lactose/galactose; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Store: Store at room temperature away from moisture and heat.




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MILLION HEALTH PHARMACEUTICALS
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Mr. Saravanan R (Proprietor)
Mobile :+917042614487
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