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Gilotrif Afatinib

Gilotrif Afatinib
Gilotrif Afatinib
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Product Code : 140
Brand Name : Gilotrif
Product Description

Gilotrif (Afatinib)

Brand Name : Gilotrif

Active Ingeridents(Generic Name) : Afatinib

Company Name: Boehringer Ingelheim

Package: 7 tabs in strips

Strength : 20mg, 30mg &  40mg


Indiacation: 
It is used in first-line treatment of patients with distinct types of metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC), developed by Boehringer Ingelheim. It acts as an irreversible covalent inhibitor of the receptor tyrosine kinases epidermal growth factor receptor (EGFR) and erbB-2 (HER2).It has received regulatory approval for use as a treatment for non-small cell lung cancer, although there is emerging evidence to support its use in other cancers such as breast cancer.

Mechanism of action:

 

Gilotrif (Afatinib)is a protein kinase inhibitor that also irreversibly inhibits human epidermal growth factor receptor 2  and epidermal growth factor receptor (EGFR) kinases. Gilotrif (Afatinib)is not only active against EGFR mutations targeted by first generation TKIs like erlotinib or gefitinib, but also against mutations such as T790M which are not sensitive to these standard therapies. Because of its additional activity against receptor 2, it is being investigated for breast cancer as well as other EGFR and receptor 2 driven cancers.

DOSAGE:

  • Gilotrif (Afatinib)is a pill, taken by mouth.

  • Take Gilotrif (Afatinib)on an empty stomach at least 1 hour before or 2 hours after a meal.

  • Take Gilotrif (Afatinib)exactly as prescribed.

  • Swallow Gilotrif (Afatinib)tablets whole with at least 8 ounces of water. Do not crush or dissolve tablets.

  • Do not change your dose or stop Gilotrif (Afatinib)unless your health care provider tells you to.

  • If you miss a dose and your next dose is due in: Less than 12 hours, take your next dose at the normal time. Do not make up the next dose.

  • 12 hours or more, take the missed dose as soon as you remember. Take your next dose at the normal time.

  • Do not take more than 1 dose of Gilotrif (Afatinib)at one time. Call your health care provider and go to the emergency room right away if you take too much.

  • Store at room temperature (68° F to 77° F); keep medication in original bottle; protect from high humidity, moisture and light.

  • The amount of Gilotrif (Afatinib)that you will receive depends on many factors, including your general health or other health problems, and the type of cancer or condition you have. Your doctor will determine your exact Gilotrif (Afatinib)dosage and schedule


SIDE EFFECTS:

The following side effects are common (occurring in greater than 30%) for patients taking Gilotrif (Afatinib):

  • Diarrhea

  • Acneiform eruption (group of skin conditions resembling acne)

  • Mouth sores,Paronychia (infection of nails),Dry mouth

These are less common side effects (occurring in 10-29%) for patients receiving Gilotrif (Afatinib):

  • Decreased appetite,Itching,Weight loss,Nose bleeds,Cystitis (bladder infection),Cheilitis (inflammation of the lips),Fever,Hypokalemia (low potassium),Conjunctivitis (pink eye),Rhinorrhea (runny nose)

  • Elevated liver enzymes

PRECAUTIONS:

  • Before starting Gilotrif (Afatinib)treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.).

  • While taking Gilotrif (Afatinib), do not receive any kind of immunization or vaccination without your doctor’s approval.

 

Store: Gilotrif (Afatinib)  room temperature away from moisture and heat

 




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MILLION HEALTH PHARMACEUTICALS
Portion A, First Floor, Old No. 131, New No. 50, Pedariyar Koil Street, Seven Wells, Chennai - 600001, Tamil Nadu, India
Phone :+917042614487
Mr. Saravanan R (Proprietor)
Mobile :+917042614487
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