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Veenat Imatinib

Veenat Imatinib
Veenat Imatinib
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Product Code : 190
Brand Name : Veenat
Product Description

Veenat  (Imatinib)

  • Brand name:    Veenat
  • Active Ingeridents(Generic Name) :  Imatinib
  • Company Name :   natco
  • Package:  10 Tabs in strip
  • Strength : 400mg

Indication:  

This medication is used to treat certain types of cancer (such as acute lymphoblastic leukemia, chronic myeloid leukemia, gastrointestinal stromal tumors, and myelodysplastic/myeloproliferative diseases). It is a chemotherapy drug that works by slowing or stopping the growth of cancer cells.

Mechanism of action:

Veenat (Imatinib) is a 2-phenyl amino pyrimidine derivative that functions as a specific inhibitor of a number of tyrosine kinase enzymes. It occupies the TK active site, leading to a decrease in activity.There are a large number of TK enzymes in the body, including the insulin receptor. Veenat (Imatinib) is specific for the TK domain in abl(the Abelson proto-oncogene), c-kit and PDGF-R (platelet-derived growth factor receptor).In chronic myelogenous leukemia, the Philadelphia chromosome leads to a fusion protein of abl with bcr(breakpoint cluster region), termed bcr-abl. As this is now aconstitutively active tyrosine kinase, Veenat (Imatinib) is used to decrease bcr-abl activity.The active sites of tyrosine kinases each have a binding site for ATP. The enzymatic activity catalyzed by a tyrosine kinase is the transfer of the terminal phosphate from ATP to tyrosine residues on its substrates, a process known as protein tyrosinephosphorylation.

  Dosage and Administration:

Take the medicine with a large glass of water and food.  This will help to avoid irritating the lining of your oesophagus (food pipe) and stomach.

Side Effects:

The most common side effects include feeling sick (nausea), diarrhea, headaches, leg aches/cramps, fluid retention, visual disturbances, itchy rash, lowered resistance to infection, bruising or bleeding, loss of appetite; weight gain, reduced number of blood cells (neutropeniathrombocytopeniaanemia), and edema. Although rare, restoration of hair color has been reported as well. Severecongestive cardiac failure is an uncommon but recognized side effect of Veenat (Imatinib) and mice treated with large doses of Veenat (Imatinib) show toxic damage to their myocardium.

Precaution:

The only known contraindication to Veenat (Imatinib) is hypersensitivity to Veenat (Imatinib). Cautions include:

  • Hepatic impairment
  • Risk of severe CHF or left ventricular dysfunction, especially in patients with comorbidities
  • Pregnancy, risk of embryo-fetal toxicity
  • Risk of fluid retention
  • Risk of growth stunting in children or adolescents

 Store:  Veenat (Imatinib)  room temperature away from moisture and heat.




MILLION HEALTH PHARMACEUTICALS
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MILLION HEALTH PHARMACEUTICALS
Portion A, First Floor, Old No. 131, New No. 50, Pedariyar Koil Street, Seven Wells, Chennai - 600001, Tamil Nadu, India
Phone :+917042614487
Mr. Saravanan R (Proprietor)
Mobile :+917042614487
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