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Home » Products » Anti Cancer Medicines » Afinitor Everolimus

Afinitor Everolimus

Afinitor Everolimus
Afinitor Everolimus
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Product Code : 170
Brand Name : Afinitor
Product Description

Afinitor (Everolimus)  

Brand name: Afinitor

Active Ingeridents(Generic Name) :Everolimus   

Company Name: Novartis Pharmaceuticals

Package: 7 tabs in a strip

Strength : 2.5mg, 5mg & 10mg

Indication:

Afinitor (Everolimus)    is  used to treat a certain type of advanced breast cancer that has already been treated with at least one other medication. Afinitor (Everolimus)    is also used to treat a certain type of cancer of the pancreas that has spread or progressed and that cannot be treated with surgery

Mechanism of action:

Afinitor (Everolimus) is a mTOR inhibitor that binds with high affinity to the FK506 binding protein-12 (FKBP-12), thereby forming a drug complex that inhibits the activation of mTOR. This inhibition reduces the activity of effectors downstream, which leads to a blockage in the progression of cells from G1 into S phase, and subsequently inducing cell growth arrest and apoptosis. Afinitor (Everolimus)   also inhibits the expression of hypoxia-inducible factor, leading to a decrease in the expression of vascular endothelial growth factor. The result of Afinitor (Everolimus)   inhibition of mTOR is a reduction in cell proliferation, angiogenesis, and glucose uptake.

 

Dosage and Administration:

  • Afinitor (Everolimus)      is given as a tablet by mouth.

  • Take at the same time each day, may be taken with or without food.

  • Swallow whole with a glass of water, do not chew or crush tablets.

  • Avoid contact with or exposure to crushed or broken tablets.

  • The amount of Afinitor (Everolimus)    that you will receive will be prescribed by your doctor based on established dosing guidelines.

 

Side effects:

Stop using Afinitor (Everolimus)   and call your doctor at once if you have: Common Afinitor (Everolimus)    side effects may include:

·         infections, cough, nosebleeds;  mouth sores, taste problems, dry mouth;  nausea, vomiting, diarrhea, constipation;  weight loss, feeling weak or tired;,  pain or swelling anywhere in your body; dry skin, rash, acne;  missed menstrual periods; unusual changes in mood or behavior; sleep problems (insomnia);  dizziness, headache; high blood sugar - increased thirst or urination, hunger, fruity breath odor, blurred vision.

Precaution:

  • Before starting Afinitor (Everolimus)    treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.).

  • Do not receive any kind of immunization or vaccination without your doctor’s approval while taking Afinitor (Everolimus)  .

Store: Afinitor (Everolimus)   room temperature away from moisture and heat




MILLION HEALTH PHARMACEUTICALS
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MILLION HEALTH PHARMACEUTICALS
Portion A, First Floor, Old No. 131, New No. 50, Pedariyar Koil Street, Seven Wells, Chennai - 600001, Tamil Nadu, India
Phone :+917042614487
Mr. Saravanan R (Proprietor)
Mobile :+917042614487
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